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Page 1
Identification and expression analysis of novel Jakmip1 transcripts.
Costa V, Conte I, Ziviello C, Casamassimi A, Alfano G, Banfi S, Ciccodicola A. Costa V, et al. Gene. 2007 Nov 1;402(1-2):1-8. doi: 10.1016/j.gene.2007.07.001. Epub 2007 Jul 14. Gene. 2007. PMID: 17761393
Recently Jakmip1 was also identified as an interacting partner of GABA(B)R1 and as a regulatory protein of GABA(B)R2 mRNA. We have confirmed that this gene is highly expressed in brain and retina tissues and it is also present at lower levels in other tissues. ...
Recently Jakmip1 was also identified as an interacting partner of GABA(B)R1 and as a regulatory protein of GABA(B)R2 mRNA. We have co …
RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons.
Vidal RL, Fuentes P, Valenzuela JI, Alvarado-Diaz CP, Ramírez OA, Kukuljan M, Couve A. Vidal RL, et al. Mol Cell Neurosci. 2012 Aug;51(1-2):1-11. doi: 10.1016/j.mcn.2012.07.007. Epub 2012 Jul 22. Mol Cell Neurosci. 2012. PMID: 22828129
The structural organization and dynamic remodeling of the cytoskeleton and its association to the secretory pathway are critical determinants of cell morphogenesis and migration. Marlin-1 (Jakmip1) is a microtubule-associated protein predominantly expressed in neurons and …
The structural organization and dynamic remodeling of the cytoskeleton and its association to the secretory pathway are critical determinant …
JAKMIP1: Translating the Message for Social Behavior.
Penney J, Tsai LH. Penney J, et al. Neuron. 2015 Dec 16;88(6):1070-1072. doi: 10.1016/j.neuron.2015.12.003. Neuron. 2015. PMID: 26687214 Free article.
In this issue of Neuron, Berg et al. (2015) uncover multifaceted roles for janus kinase and microtubule-interacting protein 1 (JAKMIP1) in regulating neuronal mRNA translation and establish JAKMIP1 knockout mice as an important model to study autism spectrum disorde …
In this issue of Neuron, Berg et al. (2015) uncover multifaceted roles for janus kinase and microtubule-interacting protein 1 (JAKMIP1 …
Cellular and subcellular localization of Marlin-1 in the brain.
Vidal RL, Valenzuela JI, Luján R, Couve A. Vidal RL, et al. BMC Neurosci. 2009 Apr 22;10:37. doi: 10.1186/1471-2202-10-37. BMC Neurosci. 2009. PMID: 19386132 Free PMC article.
Marlin-1 is expressed mainly in the central nervous system but little is known regarding its cellular and subcellular distribution in the brain. RESULTS: Here we have studied the localization of Marlin-1 in the rodent brain and cultured neurons combining immunohisto …
Marlin-1 is expressed mainly in the central nervous system but little is known regarding its cellular and subcellular distribution in the …
Using AI-Based Evolutionary Algorithms to Elucidate Adult Brain Tumor (Glioma) Etiology Associated with IDH1 for Therapeutic Target Identification.
McInerney CE, Lynn JA, Gilmore AR, Flannery T, Prise KM. McInerney CE, et al. Curr Issues Mol Biol. 2022 Jul 2;44(7):2982-3000. doi: 10.3390/cimb44070206. Curr Issues Mol Biol. 2022. PMID: 35877430 Free PMC article.
Adult brain tumors (glioma) represent a cancer of unmet need where standard-of-care is non-curative; thus, new therapies are urgently needed. ...Other non-enriched pathways included O-glycan biosynthesis, notch signaling, and signaling regulating stem cell pluripotency (PC …
Adult brain tumors (glioma) represent a cancer of unmet need where standard-of-care is non-curative; thus, new therapies are urgently …
Alcohol-dose-dependent DNA methylation and expression in the nucleus accumbens identifies coordinated regulation of synaptic genes.
Cervera-Juanes R, Wilhelm LJ, Park B, Grant KA, Ferguson B. Cervera-Juanes R, et al. Transl Psychiatry. 2017 Jan 10;7(1):e994. doi: 10.1038/tp.2016.266. Transl Psychiatry. 2017. PMID: 28072409 Free PMC article.
Expression analysis of three of the DMR-associated genes, LRP5, GPR39 and JAKMIP1, revealed significant correlations between DMR methylation and whole-gene or alternative transcript expression, supporting a functional role in regulating gene expression. ...
Expression analysis of three of the DMR-associated genes, LRP5, GPR39 and JAKMIP1, revealed significant correlations between DMR meth …
Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci.
Hedges DJ, Hamilton-Nelson KL, Sacharow SJ, Nations L, Beecham GW, Kozhekbaeva ZM, Butler BL, Cukier HN, Whitehead PL, Ma D, Jaworski JM, Nathanson L, Lee JM, Hauser SL, Oksenberg JR, Cuccaro ML, Haines JL, Gilbert JR, Pericak-Vance MA. Hedges DJ, et al. Mol Autism. 2012 Apr 2;3:2. doi: 10.1186/2040-2392-3-2. Mol Autism. 2012. PMID: 22472195 Free PMC article.
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the brain, acting primarily via the GABA receptors (GABR). Multiple lines of evidence, including altered GABA and GABA receptor expression in autistic patients, indicate that the GABAergic system ma …
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the brain, acting primarily via the GABA receptors (GABR). …
Marlin-1 is expressed in testis and associates to the cytoskeleton and GABAB receptors.
Vidal RL, Ramírez A, Castro M, Concha II, Couve A. Vidal RL, et al. J Cell Biochem. 2008 Feb 15;103(3):886-95. doi: 10.1002/jcb.21456. J Cell Biochem. 2008. PMID: 17668444
In humans and rodents, expression of Marlin-1 is predominantly restricted to the brain, but expression in lymphoid cells has also been reported. Here, we have studied the distribution of Marlin-1 in testis and spermatozoa. ...
In humans and rodents, expression of Marlin-1 is predominantly restricted to the brain, but expression in lymphoid cells has also bee …
Marlin-1, a novel RNA-binding protein associates with GABA receptors.
Couve A, Restituito S, Brandon JM, Charles KJ, Bawagan H, Freeman KB, Pangalos MN, Calver AR, Moss SJ. Couve A, et al. J Biol Chem. 2004 Apr 2;279(14):13934-43. doi: 10.1074/jbc.M311737200. Epub 2004 Jan 12. J Biol Chem. 2004. PMID: 14718537 Free article.
Here we have identified Marlin-1, a novel GABA(B) receptor-binding protein that associates specifically with the GABA(B)R1 subunit in yeast, tissue culture cells, and neurons. Marlin-1 is expressed in the brain and exhibits a granular distribution in cultured hippocampal n …
Here we have identified Marlin-1, a novel GABA(B) receptor-binding protein that associates specifically with the GABA(B)R1 subunit in yeast, …